CGI Pharmaceuticals

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City: Branford

State: Connecticut

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Country: United States

Founded out of Yale University, CGI (formerly Cellular Genomics Inc.) began operations in 2000. CGI, in conjunction with several biotech and pharmaceutical partners (Pfizer, Serono, Lilly, Affymetrix, and Schering AG), utilized a unique chemical-genetics approach known as “ASKA” (Analog Sensitive Kinase Alleles) to understand kinase function. CGI Pharmaceuticals is dedicated to the discovery and development of breakthrough small molecule therapeutics for a broad range of oncology and allergy/autoimmune/inflammatory disease (AAID) indications. The Company’s fully integrated drug discovery infrastructure comprises proprietary kinase biology and chemistry, extensive lead generation and optimization capabilities, as well as drug metabolism/pharmacokinetics (DMPK) expertise. Utilizing its comprehensive chemistry capabilities, CGI has generated a proprietary small molecule kinase inhibitor library of over 50,000 compounds (all compounds designed and synthesized by CGI). To date, CGI has been awarded 8 U.S. patents covering its novel collection of kinase inhibitors. Moreover, all three of CGI’s drug discovery and development programs are based on hits obtained from CGI’s library.

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